Three-dimensional (3D) printing of mouse primary hepatocytes to generate 3D hepatic structure
نویسندگان
چکیده
منابع مشابه
Three-dimensional (3D) printing of mouse primary hepatocytes to generate 3D hepatic structure
PURPOSE The major problem in producing artificial livers is that primary hepatocytes cannot be cultured for many days. Recently, 3-dimensional (3D) printing technology draws attention and this technology regarded as a useful tool for current cell biology. By using the 3D bio-printing, these problems can be resolved. METHODS To generate 3D bio-printed structures (25 mm × 25 mm), cells-alginate...
متن کامل3D Cultivation Techniques for Primary Human Hepatocytes
One of the main challenges in drug development is the prediction of in vivo toxicity based on in vitro data. The standard cultivation system for primary human hepatocytes is based on monolayer cultures, even if it is known that these conditions result in a loss of hepatocyte morphology and of liver-specific functions, such as drug-metabolizing enzymes and transporters. As it has been demonstrat...
متن کاملKNApSAcK-3D: a three-dimensional structure database of plant metabolites.
Studies on plant metabolites have attracted significant attention in recent years. Over the past 8 years, we have constructed a unique metabolite database, called KNApSAcK, that contains information on the relationships between metabolites and their expressing organism(s). In the present paper, we introduce KNApSAcK-3D, which contains the three-dimensional (3D) structures of all of the metaboli...
متن کاملthree-dimensional (3d) cell culture conditions, present and future improvements
conclusions our underlying hypothesis is that recapitulating the three-dimensional early embryonic structure, in order to reproduce better in vitro the three-dimensional morphogenetic-like re-arrangements, would improve cells differentiation, when in vivo transplanted; moreover, it could be used as a simplified cancer disease model and reliable drug evaluation method as well. results the proces...
متن کاملOne-Dimensional design of a three-stage axial compressor with Its 3D numerical simulation
The purpose of this study is to design a three-stage axial compressor with identical pressure ratio which makes an adequate pressure ratio and efficiency in design point conditions with rotational velocity of 38000rpm and mass flow rate of 3.2kg/s. First of all, considering some restrictions such as Dehaller number more than 0.7 in all sections of the stator and the rotor, and relative Mach num...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Surgical Treatment and Research
سال: 2017
ISSN: 2288-6575,2288-6796
DOI: 10.4174/astr.2017.92.2.67